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Suppression of Glucagon-Like Peptide-1 Release by Inhibition of Intestinal NLRP3 Inflammasome Activation in Asc(–/–) and Nlrp3(–/–) Mice

The glucagon-like peptide-1 (GLP-1) is an insulinotropic hormone secreted by intestinal enteroendocrine L-cells, which plays a crucial role in glucose control, regulation, and protection from different pathological conditions such as diabetes mellitus. The present study sought to test whether GLP-1...

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Pubblicato in:Front Physiol
Autori principali: Chen, Yu, Kidd, Jason, Bhat, Owais M., Yuan, Xinxu, Hong, Jinni, He, Xingxiang, Li, Pin-Lan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779826/
https://ncbi.nlm.nih.gov/pubmed/31632284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01213
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