Nuclear shape, protrusive behaviour and in vivo retention of human bone marrow mesenchymal stromal cells is controlled by Lamin-A/C expression

Culture expanded mesenchymal stromal cells (MSCs) are being extensively studied for therapeutic applications, including treatment of graft-versus-host disease, osteogenesis imperfecta and for enhancing engraftment of hematopoietic stem cells after transplantation. Thus far, clinical trials have show...

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Vydáno v:Sci Rep
Hlavní autoři: Dorland, Yvonne L., Cornelissen, Anne S., Kuijk, Carlijn, Tol, Simon, Hoogenboezem, Mark, van Buul, Jaap D., Nolte, Martijn A., Voermans, Carlijn, Huveneers, Stephan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779744/
https://ncbi.nlm.nih.gov/pubmed/31591420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50955-x
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