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Casein kinase-2–mediated phosphorylation increases the SUMO-dependent activity of the cytomegalovirus transactivator IE2

Many viral factors manipulate the host post-translational modification (PTM) machinery for efficient viral replication. In particular, phosphorylation and SUMOylation can distinctly regulate the activity of the human cytomegalovirus (HCMV) transactivator immediate early 2 (IE2). However, the molecul...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Tripathi, Vasvi, Chatterjee, Kiran Sankar, Das, Ranabir
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779447/
https://ncbi.nlm.nih.gov/pubmed/31371453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009601
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