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Sulfur-containing histidine compounds inhibit γ-glutamyl transpeptidase activity in human cancer cells
γ-Glutamyl transpeptidase (GGT) is an enzyme located on the surface of cellular membranes and involved in GSH metabolism and maintenance of redox homeostasis. High GGT expression on tumor cells is associated with increased cell proliferation and resistance against chemotherapy. GGT inhibitors evalua...
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| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6779435/ https://ncbi.nlm.nih.gov/pubmed/31375562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009304 |
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