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Tryptoline-Based Benzothiazoles Re-sensitize MRSA to β-Lactam Antibiotics
Resistance-modifying agents (RMAs) offer a promising solution to combat bacterial antibiotic resistance. Here we report the discovery and structure-activity relationships of a new class of RMAs with a novel tryptoline-based benzothiazole scaffold. Our most potent compound in this series (4ad) re-sen...
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| Publicado en: | Bioorg Med Chem |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6779328/ https://ncbi.nlm.nih.gov/pubmed/31521461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2019.115095 |
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