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Pathway Analysis Integrating Genome-Wide and Functional Data Identifies PLCG2 as a Candidate Gene for Age-Related Macular Degeneration
PURPOSE: Age-related macular degeneration (AMD) is the worldwide leading cause of blindness among the elderly. Although genome-wide association studies (GWAS) have identified AMD risk variants, their roles in disease etiology are not well-characterized, and they only explain a portion of AMD heritab...
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| 發表在: | Invest Ophthalmol Vis Sci |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Association for Research in Vision and Ophthalmology
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6779289/ https://ncbi.nlm.nih.gov/pubmed/31560769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.19-27827 |
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