B-1 cell-mediated modulation of M1 macrophage profile ameliorates microbicidal functions and disrupt the evasion mechanisms of Encephalitozoon cuniculi

Here, we have investigated the possible effect of B-1 cells on the activity of peritoneal macrophages in E. cuniculi infection. In the presence of B-1 cells, peritoneal macrophages had an M1 profile with showed increased phagocytic capacity and index, associated with the intense microbicidal activit...

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Udgivet i:PLoS Negl Trop Dis
Main Authors: Pereira, Adriano, Alvares-Saraiva, Anuska Marcelino, Konno, Fabiana Toshie de Camargo, Spadacci-Morena, Diva Denelle, Perez, Elizabeth Cristina, Mariano, Mario, Lallo, Maria Anete
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779274/
https://ncbi.nlm.nih.gov/pubmed/31536488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007674
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