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Glycobiology of syndecan-1 in bacterial infections

Syndecan-1 (Sdc1) is a major cell surface heparan sulfate (HS) proteoglycan of epithelial cells, a cell type targeted by many bacterial pathogens early in their pathogenesis. Loss of Sdc1 in mice is a gain-of-function mutation that significantly decreases the susceptibility to several bacterial infe...

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Detalhes bibliográficos
Publicado no:Biochem Soc Trans
Main Authors: Aquino, Rafael S., Teng, Yvonne Hui-Fang, Park, Pyong Woo
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779160/
https://ncbi.nlm.nih.gov/pubmed/29523771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20170395
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