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Transformation of N,N-Dimethylaniline N-Oxides into Diverse Tetrahydroquinoline Scaffolds via Formal Povarov Reactions

A one-pot protocol for the assembly of diversely functionalized tetrahydro-, hexahydrofuro-, hexahydropyrano-, and tetrahydrobenzofuroquinolines from N,N-dimethylaniline N-oxides and various electron-rich olefins in a tandem Polonovski–Povarov sequence is reported. Following activation of the N–O bo...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Bush, Timothy S., Yap, Glenn P. A., Chain, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779048/
https://ncbi.nlm.nih.gov/pubmed/30109939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.8b02318
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