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Trypsin Pre-Treatment Combined with Growth-Factor Functionalized Self-Assembling Peptide Hydrogel Improves Cartilage Repair in Rabbit Model

The objective of this study was to improve cartilage repair and integration using self-assembling KLD hydrogel functionalized with platelet derived growth factor-BB and heparin-binding insulin like growth factor-1 with associated enzymatic trypsin pre-treatment of the native cartilage. Bilateral ost...

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Bibliographic Details
Published in:J Orthop Res
Main Authors: Zanotto, Gustavo, Liebesny, Paul, Barrett, Myra, Zlotnick, Hannah, Grodzinsky, Alan, Frisbie, David
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778710/
https://ncbi.nlm.nih.gov/pubmed/31318103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.24414
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