Growth Hormone-Releasing Hormone Receptor Antagonist Modulates Lung Inflammation and Fibrosis due to Bleomycin

PURPOSE: Growth hormone-releasing hormone (GHRH) is a 44-amino acid peptide that regulates growth hormone (GH) secretion. We hypothesized that a GHRH receptor (GHRH-R) antagonist, MIA-602, would inhibit bleomycin-induced lung inflammation and/or fibrosis in C57Bl/6J mice. METHODS: We tested whether...

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Detalhes bibliográficos
Publicado no:Lung
Main Authors: Zhang, Chongxu, Cai, Renzhi, Lazerson, Aaron, Delcroix, Gaetan, Wangpaichitr, Medhi, Mirsaeidi, Mehdi, Griswold, Anthony J., Schally, Andrew V., Jackson, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2019
Assuntos:
Interstitial Lung Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778540/
https://ncbi.nlm.nih.gov/pubmed/31392398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00408-019-00257-w
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