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Mouse embryo geometry drives formation of robust signaling gradients through receptor localization

Morphogen signals are essential for cell fate specification during embryogenesis. Some receptors that sense these morphogens are known to localize to only the apical or basolateral membrane of polarized cell lines in vitro. How such localization affects morphogen sensing and patterning in the develo...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhang, Zhechun, Zwick, Steven, Loew, Ethan, Grimley, Joshua S., Ramanathan, Sharad
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778081/
https://ncbi.nlm.nih.gov/pubmed/31586065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12533-7
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