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Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

Alzheimer disease (AD) is a heterogeneous disease with a complex pathobiology. The presence of extracellular amyloid-β deposition as neuritic plaques and intracellular accumulation of hyperphosphorylated tau as neurofibrillary tangles remain the primary neuropathologic criteria for AD diagnosis. How...

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Bibliografski detalji
Izdano u:Cell
Glavni autori: Long, Justin M., Holtzman, David M
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778042/
https://ncbi.nlm.nih.gov/pubmed/31564456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.09.001
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