Clopidogrel Drug Interactions and Serious Bleeding: Generating Real World Evidence via Automated High-Throughput Pharmacoepidemiologic Screening

Few population-based studies have examined bleeding associated with clopidogrel drug-drug interactions (DDIs). We sought to identify precipitant drugs taken concomitantly with clopidogrel (an object drug) that increased serious bleeding rates. We screened 2000–2015 Optum commercial health insurance...

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Pubblicato in:Clin Pharmacol Ther
Autori principali: Leonard, Charles E., Zhou, Meijia, Brensinger, Colleen M., Bilker, Warren B., Soprano, Samantha E., Nguyen, Thanh Phuong Pham, Nam, Young Hee, Cohen, Jordana B., Hennessy, Sean
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777989/
https://ncbi.nlm.nih.gov/pubmed/31106397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1507
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