NHR-14 loss of function couples intestinal iron uptake with innate immunity in C. elegans through PQM-1 signaling

Iron is essential for survival of most organisms. All organisms have thus developed mechanisms to sense, acquire and sequester iron. In C. elegans, iron uptake and sequestration are regulated by HIF-1. We previously showed that hif-1 mutants are developmentally delayed when grown under iron limitati...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Rajan, Malini, Anderson, Cole P, Rindler, Paul M, Romney, Steven Joshua, Ferreira dos Santos, Maria C, Gertz, Jason, Leibold, Elizabeth A
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2019
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777940/
https://ncbi.nlm.nih.gov/pubmed/31532389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44674
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