Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human retina-on-a-chip platform

The devastating effects and incurable nature of hereditary and sporadic retinal diseases such as Stargardt disease, age-related macular degeneration or retinitis pigmentosa urgently require the development of new therapeutic strategies. Additionally, a high prevalence of retinal toxicities is becomi...

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Vydáno v:eLife
Hlavní autoři: Achberger, Kevin, Probst, Christopher, Haderspeck, Jasmin, Bolz, Sylvia, Rogal, Julia, Chuchuy, Johanna, Nikolova, Marina, Cora, Virginia, Antkowiak, Lena, Haq, Wadood, Shen, Nian, Schenke-Layland, Katja, Ueffing, Marius, Liebau, Stefan, Loskill, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2019
Témata:
Human Biology and Medicine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777939/
https://ncbi.nlm.nih.gov/pubmed/31451149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.46188
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