Kinetic characteristics of propofol-induced inhibition of electron-transfer chain and fatty acid oxidation in human and rodent skeletal and cardiac muscles

INTRODUCTION: Propofol causes a profound inhibition of fatty acid oxidation and reduces spare electron transfer chain capacity in a range of human and rodent cells and tissues–a feature that might be related to the pathogenesis of Propofol Infusion Syndrome. We aimed to explore the mechanism of prop...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Urban, Tomáš, Waldauf, Petr, Krajčová, Adéla, Jiroutková, Kateřina, Halačová, Milada, Džupa, Valér, Janoušek, Libor, Pokorná, Eva, Duška, František
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777831/
https://ncbi.nlm.nih.gov/pubmed/31584947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217254
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