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NOX4 modulates macrophage phenotype and mitochondrial biogenesis in asbestosis
Macrophage activation is implicated in the development of pulmonary fibrosis by generation of profibrotic molecules. Although NADPH oxidase 4 (NOX4) is known to contribute to pulmonary fibrosis, its effects on macrophage activation and mitochondrial redox signaling are unclear. Here, we show that NO...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6777818/ https://ncbi.nlm.nih.gov/pubmed/31434799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126551 |
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