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Ceftiofur formulation differentially affects the intestinal drug concentration, resistance of fecal Escherichia coli, and the microbiome of steers

Antimicrobial drug concentrations in the gastrointestinal tract likely drive antimicrobial resistance in enteric bacteria. Our objective was to determine the concentration of ceftiofur and its metabolites in the gastrointestinal tract of steers treated with ceftiofur crystalline-free acid (CCFA) or...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Foster, Derek M., Jacob, Megan E., Farmer, Kyle A., Callahan, Benjamin J., Theriot, Casey M., Kathariou, Sophia, Cernicchiaro, Natalia, Prange, Timo, Papich, Mark G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777789/
https://ncbi.nlm.nih.gov/pubmed/31584976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0223378
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