Inhibition of miR-328–3p Impairs Cancer Stem Cell Function and Prevents Metastasis in Ovarian Cancer

Cancer stem cells (CSC) play a central role in cancer metastasis and development of drug resistance. miRNA are important in regulating CSC properties and are considered potential therapeutic targets. Here we report that miR-328–3p (miR-328) is significantly upregulated in ovarian CSC. High expressio...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Srivastava, Amit K., Banerjee, Ananya, Cui, Tiantian, Han, Chunhua, Cai, Shurui, Liu, Lu, Wu, Dayong, Cui, Ri, Li, Zaibo, Zhang, Xiaoli, Xie, Guozhen, Selvendiran, Karuppaiyah, Patnaik, Srinivas, Karpf, Adam R., Liu, Jinsong, Cohn, David E., Wang, Qi-En
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777340/
https://ncbi.nlm.nih.gov/pubmed/30894370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-3668
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