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Protease-activated receptor 2 protects against myocardial ischemia-reperfusion injury through the lipoxygenase pathway and TRPV1 channels

This study tests the hypothesis that the lipoxygenase (LOX) pathway mediates protease-activated receptor (PAR) 2-induced activation of the transient receptor potential vanilloid receptor 1 (TRPV1) to protect the heart from ischemia/reperfusion (I/R) injury. SLIGRL, a PAR2 activating peptide, was adm...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Zhong, Beihua, Ma, Shuangtao, Wang, Donna H.
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777326/
https://ncbi.nlm.nih.gov/pubmed/31602241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.7987
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