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Sphingosine-1-phosphate induces islet β-cell proliferation and decreases cell apoptosis in high-fat diet/streptozotocin diabetic mice

Sphingosine-1-phosphate (S1P) has been reported to enhance the function of islet β-cells, providing a potential therapeutic target for diabetes mellitus. In the present study, the effects of S1P on the proliferation and apoptosis of β-cells in type 2 diabetic mice were investigated. The mice were ad...

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Publicado en:Exp Ther Med
Autores principales: He, Yizhi, Shi, Bingyin, Zhao, Xinrui, Sui, Jing
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777293/
https://ncbi.nlm.nih.gov/pubmed/31602216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.7999
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