Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial

IMPORTANCE: Experimental data suggest that intravenous vitamin C may attenuate inflammation and vascular injury associated with sepsis and acute respiratory distress syndrome (ARDS). OBJECTIVE: To determine the effect of intravenous vitamin C infusion on organ failure scores and biological markers o...

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Détails bibliographiques
Publié dans:JAMA
Auteurs principaux: Fowler, Alpha A., Truwit, Jonathon D., Hite, R. Duncan, Morris, Peter E., DeWilde, Christine, Priday, Anna, Fisher, Bernard, Thacker, Leroy R., Natarajan, Ramesh, Brophy, Donald F., Sculthorpe, Robin, Nanchal, Rahul, Syed, Aamer, Sturgill, Jamie, Martin, Greg S., Sevransky, Jonathan, Kashiouris, Markos, Hamman, Stella, Egan, Katherine F., Hastings, Andrei, Spencer, Wendy, Tench, Shawnda, Mehkri, Omar, Bindas, James, Duggal, Abhijit, Graf, Jeanette, Zellner, Stephanie, Yanny, Lynda, McPolin, Catherine, Hollrith, Tonya, Kramer, David, Ojielo, Charles, Damm, Tessa, Cassity, Evan, Wieliczko, Aleksandra, Halquist, Matthew
Format: Artigo
Langue:Inglês
Publié: American Medical Association 2019
Sujets:
Preliminary Communication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777268/
https://ncbi.nlm.nih.gov/pubmed/31573637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2019.11825
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