High mobility group box protein 1 neutralization therapy in ovine bacteremia: Lessons learned from an ovine septic shock model incorporating intensive care support

Sepsis is a highly complex and often fatal syndrome which varies widely in its clinical manifestations, and therapies that target the underlying uncontrolled immune status in sepsis are needed. The failure of preclinical approaches to provide significant sepsis survival benefit in the clinic is ofte...

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Publicado en:Exp Ther Med
Main Authors: Stevens, Natalie E., Nash, Coralie H., Fraser, Cara K., Kuchel, Tim R., Maiden, Matthew J., Chapman, Marianne J., Diener, Kerrilyn R., Hayball, John D.
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777221/
https://ncbi.nlm.nih.gov/pubmed/31602200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.7961
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