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Impaired frontostriatal functional connectivity among chronic opioid using pain patients is associated with dysregulated affect.

Preclinical studies have shown effects of chronic exposure to addictive drugs on glutamatergic-mediated neuroplasticity in frontostriatal circuitry. These initial findings have been paralleled by human fMRI research demonstrating weaker frontostriatal resting-state functional connectivity (rsFC) amo...

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Detalhes bibliográficos
Publicado no:Addict Biol
Main Authors: McConnell, Patrick A., Garland, Eric, Zubieta, Jon-Kar, Newman-Norlund, Roger, Powers, Shannon, Froeliger, Brett
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776713/
https://ncbi.nlm.nih.gov/pubmed/30945801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12743
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