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Integrating subgroups with mixed-type endpoints in early phase oncology trials

Testing anti-cancer agents with multiple disease subtypes is challenging and it becomes more complicated when the subgroups have different types of endpoints (such as binary endpoints of tumor response and progression-free survival endpoints). When this occurs, one common approach in oncology is to...

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Detalhes bibliográficos
Publicado no:Stat Methods Med Res
Main Authors: Zhao, Lili, Koschmann, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776708/
https://ncbi.nlm.nih.gov/pubmed/30945609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280219840050
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