Inhibition of Rac1-dependent forgetting alleviates memory deficits in animal models of Alzheimer’s disease

Accelerated forgetting has been identified as a feature of Alzheimer’s disease (AD), but the therapeutic efficacy of the manipulation of biological mechanisms of forgetting has not been assessed in AD animal models. Ras-related C3 botulinum toxin substrate 1 (Rac1), a small GTPase, has been shown to...

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Vydáno v:Protein Cell
Hlavní autoři: Wu, Wenjuan, Du, Shuwen, Shi, Wei, Liu, Yunlong, Hu, Ying, Xie, Zuolei, Yao, Xinsheng, Liu, Zhenyu, Ma, Weiwei, Xu, Lin, Ma, Chao, Zhong, Yi
Médium: Artigo
Jazyk:Inglês
Vydáno: Higher Education Press 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776562/
https://ncbi.nlm.nih.gov/pubmed/31321704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-019-0641-0
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