Intranasal acellular pertussis vaccine provides mucosal immunity and protects mice from Bordetella pertussis

Current acellular pertussis vaccines fall short of optimal protection against the human respiratory pathogen Bordetella pertussis resulting in increased incidence of a previously controlled vaccine- preventable disease. Natural infection is known to induce a protective mucosal immunity. Therefore, i...

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Publicado en:NPJ Vaccines
Autores principales: Boehm, Dylan T., Wolf, M. Allison, Hall, Jesse M., Wong, Ting Y., Sen-Kilic, Emel, Basinger, Hayden D., Dziadowicz, Sebastian A., Gutierrez, Maria de la Paz, Blackwood, Catherine B., Bradford, Shelby D., Begley, Katherine A., Witt, William T., Varney, Melinda E., Barbier, Mariette, Damron, F. Heath
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776550/
https://ncbi.nlm.nih.gov/pubmed/31602318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-019-0136-2
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