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A novel miRNA-4484 is up-regulated on microarray and associated with increased MMP-21 expression in serum of systemic sclerosis patients

Systemic sclerosis (SSc) is a complex, heterogeneous connective tissue disease, characterized by fibrosis and ECM deposition in skin and internal organs, autoimmunity, and changes in the microvasculature. Profiling of circulating miRNAs in serum has been found to be changed in pathological states, c...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rusek, Marta, Michalska-Jakubus, Małgorzata, Kowal, Małgorzata, Bełtowski, Jerzy, Krasowska, Dorota
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776520/
https://ncbi.nlm.nih.gov/pubmed/31582779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50695-y
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