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Centrosomal and ciliary targeting of CCDC66 requires cooperative action of centriolar satellites, microtubules and molecular motors

Mammalian centrosomes and cilia play key roles in many cellular processes and their deregulation is linked to cancer and ciliopathies. Spatiotemporal regulation of their biogenesis and function in response to physiological stimuli requires timely protein targeting. This can occur by different pathwa...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Conkar, Deniz, Bayraktar, Halil, Firat-Karalar, Elif Nur
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776500/
https://ncbi.nlm.nih.gov/pubmed/31582766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50530-4
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