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Dopamine-melanin nanoparticles scavenge reactive oxygen and nitrogen species and activate autophagy for osteoarthritis therapy

Anti-oxidative agents hold great potential in osteoarthritis (OA) therapy. However, most radical scavengers have poor biocompatibility and potential cytotoxicity, which limit their applications. Herein we explore dopamine melanin (DM) nanoparticles as a novel scavenger of reactive oxygen species (RO...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nanoscale
Hauptverfasser: Zhong, Gang, Yang, Xueyuan, Jiang, Xianfang, Kumar, Anil, Long, Huiping, Xie, Jin, Zheng, Li, Zhao, Jinmin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776464/
https://ncbi.nlm.nih.gov/pubmed/31173033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9nr03060c
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