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RPL22L1 induction in colorectal cancer is associated with poor prognosis and 5-FU resistance

We have previously demonstrated that loss of the tumor suppressive activity of ribosomal protein (RP) RPL22 predisposes to development of leukemia in mouse models and aggressive disease in human patients; however, the role of RPL22 in solid tumors, specifically colorectal cancer (CRC), had not been...

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Veröffentlicht in:PLoS One
Hauptverfasser: Rao, Shuyun, Peri, Suraj, Hoffmann, Jens, Cai, Kathy Q., Harris, Bryan, Rhodes, Michele, Connolly, Denise C., Testa, Joseph R., Wiest, David L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776433/
https://ncbi.nlm.nih.gov/pubmed/31581233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0222392
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