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Ultra-deep sequencing reveals pre-mRNA splicing as a sequence driven high-fidelity process

Alternative splicing diversifies mRNA transcripts in human cells. While the spliceosome pairs exons with a high degree of accuracy, the rates of rare aberrant and non-canonical pre-mRNA splicing have not been evaluated at the nucleotide level to determine the quantity and identity of these events ac...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Reynolds, Derrick J., Hertel, Klemens J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776343/
https://ncbi.nlm.nih.gov/pubmed/31581208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0223132
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