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Influenza virus polymerase subunits co-evolve to ensure proper levels of dimerization of the heterotrimer
The influenza A virus RNA-dependent RNA polymerase complex consists in three subunits, PB2, PB1 and PA, that perform transcription and replication of the viral genome through very distinct mechanisms. Biochemical and structural studies have revealed that the polymerase can adopt multiple conformatio...
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| Publicado no: | PLoS Pathog |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6776259/ https://ncbi.nlm.nih.gov/pubmed/31581279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008034 |
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