VLA-4 mediated adhesion of melanoma cells on the blood–brain barrier is the critical cue for melanoma cell intercalation and barrier disruption

Melanoma is the most aggressive skin cancer in humans. One severe complication is the formation of brain metastasis, which requires extravasation of melanoma cells across the tight blood–brain barrier (BBB). Previously, VLA-4 has been assigned a role for the adhesive interaction of melanoma cells wi...

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Veröffentlicht in:J Cereb Blood Flow Metab
Hauptverfasser: García-Martín, Ana B, Zwicky, Pascale, Gruber, Thomas, Matti, Christoph, Moalli, Federica, Stein, Jens V, Francisco, David, Enzmann, Gaby, Levesque, Mitchell P, Hewer, Ekkehard, Lyck, Ruth
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2018
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775593/
https://ncbi.nlm.nih.gov/pubmed/29762071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X18775887
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