Fermentative Production of N-Alkylated Glycine Derivatives by Recombinant Corynebacterium glutamicum Using a Mutant of Imine Reductase DpkA From Pseudomonas putida

Sarcosine, an N-methylated amino acid, shows potential as antipsychotic, and serves as building block for peptide-based drugs, and acts as detergent when acetylated. N-methylated amino acids are mainly produced chemically or by biocatalysis, with either low yields or high costs for co-factor regener...

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Bibliographische Detailangaben
Veröffentlicht in:Front Bioeng Biotechnol
Hauptverfasser: Mindt, Melanie, Hannibal, Silvin, Heuser, Maria, Risse, Joe Max, Sasikumar, Keerthi, Nampoothiri, K. Madhavan, Wendisch, Volker F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Bioengineering and Biotechnology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775277/
https://ncbi.nlm.nih.gov/pubmed/31616665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00232
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