Fermentative Production of N-Alkylated Glycine Derivatives by Recombinant Corynebacterium glutamicum Using a Mutant of Imine Reductase DpkA From Pseudomonas putida

Sarcosine, an N-methylated amino acid, shows potential as antipsychotic, and serves as building block for peptide-based drugs, and acts as detergent when acetylated. N-methylated amino acids are mainly produced chemically or by biocatalysis, with either low yields or high costs for co-factor regener...

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Vydáno v:Front Bioeng Biotechnol
Hlavní autoři: Mindt, Melanie, Hannibal, Silvin, Heuser, Maria, Risse, Joe Max, Sasikumar, Keerthi, Nampoothiri, K. Madhavan, Wendisch, Volker F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Bioengineering and Biotechnology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775277/
https://ncbi.nlm.nih.gov/pubmed/31616665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00232
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