Machine Learning Predicts Accurately Mycobacterium tuberculosis Drug Resistance From Whole Genome Sequencing Data

Background: Tuberculosis disease, caused by Mycobacterium tuberculosis, is a major public health problem. The emergence of M. tuberculosis strains resistant to existing treatments threatens to derail control efforts. Resistance is mainly conferred by mutations in genes coding for drug targets or con...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Deelder, Wouter, Christakoudi, Sofia, Phelan, Jody, Benavente, Ernest Diez, Campino, Susana, McNerney, Ruth, Palla, Luigi, Clark, Taane G.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775242/
https://ncbi.nlm.nih.gov/pubmed/31616478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00922
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