BioSAXS Measurements Reveal That Two Antimicrobial Peptides Induce Similar Molecular Changes in Gram-Negative and Gram-Positive Bacteria

Two highly active short broad-spectrum AMPs (14D and 69D) with unknown mode of action have been investigated in regards to their effect against the Gram-negative bacteria Escherichia coli and the Gram-positive bacteria methicillin-resistant Staphylococcus aureus (MRSA). Minimal inhibitory concentrat...

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Veröffentlicht in:Front Pharmacol
Hauptverfasser: von Gundlach, Andreas, Ashby, Martin P., Gani, Jurnorain, Lopez-Perez, Paula Matilde, Cookson, Alan Roy, Ann Huws, Sharon, Rumancev, Christoph, Garamus, Vasil M., Mikut, Ralf, Rosenhahn, Axel, Hilpert, Kai
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775230/
https://ncbi.nlm.nih.gov/pubmed/31616307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01127
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