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A Framework for Annotation of Antigen Specificities in High-Throughput T-Cell Repertoire Sequencing Studies

Recently developed molecular methods allow large-scale profiling of T-cell receptor (TCR) sequences that encode for antigen specificity and immunological memory of these cells. However, it is well-known that the even unperturbed TCR repertoire structure is extremely complex due to the high diversity...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Pogorelyy, Mikhail V., Shugay, Mikhail
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775185/
https://ncbi.nlm.nih.gov/pubmed/31616409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02159
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