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Scalable analysis of cell type composition from single-cell transcriptomics using deep recurrent learning

Recent advances in large-scale single cell RNA-seq enable fine-grained characterization of phenotypically distinct cellular states within heterogeneous tissues. We present scScope, a scalable deep-learning based approach that can accurately and rapidly identify cell-type composition from millions of...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Deng, Yue, Bao, Feng, Dai, Qionghai, Wu, Lani F., Altschuler, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774994/
https://ncbi.nlm.nih.gov/pubmed/30886411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-019-0353-7
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