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Fluid shear stress stimulates breast cancer cells to display invasive and chemoresistant phenotypes while upregulating PLAU in a 3D bioreactor
Breast cancer cells experience a range of shear stresses in the tumor microenvironment (TME). However most current in vitro three-dimensional (3D) models fail to systematically probe the effects of this biophysical stimuli on cancer cell metastasis, proliferation and chemoresistance. To investigate...
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| Pubblicato in: | Biotechnol Bioeng |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6774895/ https://ncbi.nlm.nih.gov/pubmed/31317530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.27119 |
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