High specificity and sensitivity of Zika EDIII-based ELISA diagnosis highlighted by a large human reference panel

BACKGROUND: Zika virus (ZIKV) and Dengue virus (DENV) are often co-endemic. The high protein-sequence homology of flaviviruses renders IgG induced by and directed against them highly cross-reactive against their antigen(s), as observed on a large set of sera, leading to poorly reliable sero-diagnosi...

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Veröffentlicht in:PLoS Negl Trop Dis
Hauptverfasser: Denis, Jessica, Attoumani, Sarah, Gravier, Patrick, Tenebray, Bernard, Garnier, Annabelle, Briolant, Sébastien, de Laval, Franck, Chastres, Véronique, Grard, Gilda, Leparc-Goffart, Isabelle, Coutard, Bruno, Badaut, Cyril
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774568/
https://ncbi.nlm.nih.gov/pubmed/31539394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007747
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