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Harnessing enzyme plasticity for the synthesis of oxygenated sesquiterpenoids

8-Methoxy-γ-humulene, (E)-8-methoxy-β-farnesene, 12-methoxy-β-sesquiphellandrene and 12-methoxyzingiberene can be synthesised in amorphadiene synthase-catalysed reactions from 8- and 12-methoxyfarnesyl diphosphates due to the highly plastic yet tightly controlled carbocationic chemistry of this sesq...

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Bibliografiske detaljer
Udgivet i:Beilstein J Org Chem
Main Authors: Demiray, Melodi, Miller, David J, Allemann, Rudolf K
Format: Artigo
Sprog:Inglês
Udgivet: Beilstein-Institut 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774066/
https://ncbi.nlm.nih.gov/pubmed/31598175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.215
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