Dihydropyrimidine Dehydrogenase Levels in Colorectal Cancer Cells Treated with a Combination of Heat Shock Protein 90 Inhibitor and Oxaliplatin or Capecitabine

Purpose: Dihydropyrimidine dehydrogenase (DPD) is the principal enzyme in the catabolism of fluoropyrimidine drugs including capecitabine. A recent report has suggested that oxaliplatin chemotherapy is associated with elevated DPD levels and chemoresistance pattern. As a newly developed chemotherape...

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Detalhes bibliográficos
Publicado no:Adv Pharm Bull
Main Authors: Mohammadian, Mahshid, Zeynali-Moghaddam, Shima, Khadem Ansari, Mohammad Hassan, Rasmi, Yousef, Fathi Azarbayjani, Anahita, Kheradmand, Fatemeh
Formato: Artigo
Idioma:Inglês
Publicado em: Tabriz University of Medical Sciences 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773945/
https://ncbi.nlm.nih.gov/pubmed/31592113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2019.052
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