Synergetic Impact of Combined 5-Fluorouracil and Rutin on Apoptosis in PC3 Cancer Cells through the Modulation of P53 Gene Expression

Purpose: Prostate cancer is as far the most prevalent male cancer. Rutin (a glycoside from quercetin flavonoid) displays antioxidant activity leading to cell apoptosis. Combined effects of rutin with the widely used anti-cancer drug, 5-fluorouracil (5-FU), on prostate cancer cell line (PC3) was inve...

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Detalhes bibliográficos
Publicado no:Adv Pharm Bull
Main Authors: Satari, Atefeh, Amini, Sayed Asadollah, Raeisi, Elham, Lemoigne, Yves, Heidarian, Esfandiar
Formato: Artigo
Idioma:Inglês
Publicado em: Tabriz University of Medical Sciences 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773939/
https://ncbi.nlm.nih.gov/pubmed/31592435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2019.055
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