Understanding the Origin and Diversity of Macrophages to Tailor Their Targeting in Solid Cancers

Tumor-associated macrophages (TAMs) are a major component of the tumor immune microenvironment (TIME) and are associated with a poor prognostic factor in several cancers. TAMs promote tumor growth by facilitating immunosuppression, angiogenesis, and inflammation, and can promote tumor recurrence pos...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Kielbassa, Karoline, Vegna, Serena, Ramirez, Christel, Akkari, Leila
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773830/
https://ncbi.nlm.nih.gov/pubmed/31611871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02215
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