Characterization of TCF3 rearrangements in pediatric B-lymphoblastic leukemia/lymphoma by mate-pair sequencing (MPseq) identifies complex genomic rearrangements and a novel TCF3/TEF gene fusion

The TCF3/PBX1 gene fusion is a recurrent genetic abnormality in pediatric B-lymphoblastic leukemia/lymphoma (B-ALL/LBL). While dual-color, dual-fusion fluorescence in situ hybridization (D-FISH) probes can detect TCF3/PBX1 fusions, further characterization of atypical TCF3 FISH patterns as indicated...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood Cancer J
Prif Awduron: Rowsey, Ross A., Smoley, Stephanie A., Williamson, Cynthia M., Vasmatzis, George, Smadbeck, James B., Ning, Yi, Greipp, Patricia T., Hoppman, Nicole L., Baughn, Linda B., Ketterling, Rhett P., Peterson, Jess F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773761/
https://ncbi.nlm.nih.gov/pubmed/31575852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-019-0239-z
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg