Characterization and functional analysis of two novel 3-hydroxy-3-methylglutaryl-coenzyme A reductase genes (GbHMGR2 and GbHMGR3) from Ginkgo biloba

Terpene trilactones (TTLs) are the main secondary metabolites of Ginkgo biloba. As one of the rate-limiting enzymes in the mevalonic acid (MVA) pathway of TTL biosynthesis, 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR) catalyzes the 3-hydroxy-3-methylglutaryl coenzyme A to form MVA. In this...

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Publicat a:Sci Rep
Autors principals: Rao, Shen, Meng, Xiangxiang, Liao, Yongling, Yu, Tian, Cao, Jie, Tan, Junping, Xu, Feng, Cheng, Shuiyuan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773693/
https://ncbi.nlm.nih.gov/pubmed/31575936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50629-8
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