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A review of dupilumab in the treatment of atopic diseases
Dupilumab is a fully human monoclonal IgG4 antibody directed against the alpha subunit of the IL-4 receptor and prevents the signaling of IL-4 and IL-13, two type 2 cytokines known to be important drivers of atopic diseases. In March of 2017, the United States Food and Drug Administration (FDA) appr...
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| Publicado no: | Hum Vaccin Immunother |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6773424/ https://ncbi.nlm.nih.gov/pubmed/30785362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2019.1582403 |
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