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Immunogenicity and safety of an investigational tetravalent recombinant subunit vaccine for dengue: results of a Phase I randomized clinical trial in flavivirus-naïve adults

There is an unmet medical need for vaccines to prevent dengue. V180 is an investigational recombinant subunit vaccine that consists of truncated dengue envelope proteins (DEN-80E) for all 4 serotypes. Three dosage levels of the tetravalent DEN-80E antigens were assessed in a randomized, placebo-cont...

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Bibliografiske detaljer
Udgivet i:Hum Vaccin Immunother
Main Authors: Manoff, Susan B., Sausser, Michele, Falk Russell, Amy, Martin, Jason, Radley, David, Hyatt, Donna, Roberts, Christine C., Lickliter, Jason, Krishnarajah, Janakan, Bett, Andrew, Dubey, Sheri, Finn, Tyler, Coller, Beth-Ann
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773383/
https://ncbi.nlm.nih.gov/pubmed/30427741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2018.1546523
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